Repression of essential cell cycle genes increases cellular fitness

A network of transcription factors (TFs) coordinates transcription with cell cycle events in eukaryotes. Most TFs in the network are phosphorylated by cyclin-dependent kinase (CDK), which limits their activities during the cell cycle. Here, we investigate the physiological consequences of disrupting...

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Detalles Bibliográficos
Autores principales: Conti, Michelle M., Ghizzoni, Julie M., Gil-Bona, Ana, Wang, Wen, Costanzo, Michael, Li, Rui, Flynn, Mackenzie J., Zhu, Lihua Julie, Myers, Chad L., Boone, Charles, Andrews, Brenda J., Benanti, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462756/
https://www.ncbi.nlm.nih.gov/pubmed/36037231
http://dx.doi.org/10.1371/journal.pgen.1010349

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