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Accounting for multiple imputation-induced variability for differential analysis in mass spectrometry-based label-free quantitative proteomics
Imputing missing values is common practice in label-free quantitative proteomics. Imputation aims at replacing a missing value with a user-defined one. However, the imputation itself may not be optimally considered downstream of the imputation process, as imputed datasets are often considered as if...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462777/ https://www.ncbi.nlm.nih.gov/pubmed/36037245 http://dx.doi.org/10.1371/journal.pcbi.1010420 |