Mesenchymal Stromal Cells Overexpressing Farnesoid X Receptor Exert Cardioprotective Effects Against Acute Ischemic Heart Injury by Binding Endogenous Bile Acids (Adv. Sci. 24/2022)

Mesenchymal Stromal Cells In article number 2200431, Wenjun Yan, Ling Tao, and co‐workers report a novel strategy for improving the curative effect of mesenchymal stromal cell (MSC)‐based therapy for myocardial infarction that is achieved by bile acid‐ arnesoid X receptor (FXR) axis activation. FXR...

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Detalles Bibliográficos
Autores principales: Xia, Yunlong, Xu, Xinyue, Guo, Yongzhen, Lin, Chen, Xu, Xiaoming, Zhang, Fuyang, Fan, Miaomiao, Qi, Tingting, Li, Congye, Hu, Guangyu, Peng, Lu, Wang, Shan, Zhang, Ling, Hai, Chunxu, Liu, Rui, Yan, Wenjun, Tao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Frontispiece
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462841/
http://dx.doi.org/10.1002/advs.202270152
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author Xia, Yunlong
Xu, Xinyue
Guo, Yongzhen
Lin, Chen
Xu, Xiaoming
Zhang, Fuyang
Fan, Miaomiao
Qi, Tingting
Li, Congye
Hu, Guangyu
Peng, Lu
Wang, Shan
Zhang, Ling
Hai, Chunxu
Liu, Rui
Yan, Wenjun
Tao, Ling
author_facet Xia, Yunlong
Xu, Xinyue
Guo, Yongzhen
Lin, Chen
Xu, Xiaoming
Zhang, Fuyang
Fan, Miaomiao
Qi, Tingting
Li, Congye
Hu, Guangyu
Peng, Lu
Wang, Shan
Zhang, Ling
Hai, Chunxu
Liu, Rui
Yan, Wenjun
Tao, Ling
author_sort Xia, Yunlong
collection PubMed
description Mesenchymal Stromal Cells In article number 2200431, Wenjun Yan, Ling Tao, and co‐workers report a novel strategy for improving the curative effect of mesenchymal stromal cell (MSC)‐based therapy for myocardial infarction that is achieved by bile acid‐ arnesoid X receptor (FXR) axis activation. FXR overexpression in MSC facilitates the response of MSC to endogenous bile acid signals, thus enhancing the survival and paracrine angiogenesis of MSC. [Image: see text]
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spelling pubmed-94628412022-09-28 Mesenchymal Stromal Cells Overexpressing Farnesoid X Receptor Exert Cardioprotective Effects Against Acute Ischemic Heart Injury by Binding Endogenous Bile Acids (Adv. Sci. 24/2022) Xia, Yunlong Xu, Xinyue Guo, Yongzhen Lin, Chen Xu, Xiaoming Zhang, Fuyang Fan, Miaomiao Qi, Tingting Li, Congye Hu, Guangyu Peng, Lu Wang, Shan Zhang, Ling Hai, Chunxu Liu, Rui Yan, Wenjun Tao, Ling Adv Sci (Weinh) Frontispiece Mesenchymal Stromal Cells In article number 2200431, Wenjun Yan, Ling Tao, and co‐workers report a novel strategy for improving the curative effect of mesenchymal stromal cell (MSC)‐based therapy for myocardial infarction that is achieved by bile acid‐ arnesoid X receptor (FXR) axis activation. FXR overexpression in MSC facilitates the response of MSC to endogenous bile acid signals, thus enhancing the survival and paracrine angiogenesis of MSC. [Image: see text] John Wiley and Sons Inc. 2022-08-25 /pmc/articles/PMC9462841/ http://dx.doi.org/10.1002/advs.202270152 Text en © 2022 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Frontispiece
Xia, Yunlong
Xu, Xinyue
Guo, Yongzhen
Lin, Chen
Xu, Xiaoming
Zhang, Fuyang
Fan, Miaomiao
Qi, Tingting
Li, Congye
Hu, Guangyu
Peng, Lu
Wang, Shan
Zhang, Ling
Hai, Chunxu
Liu, Rui
Yan, Wenjun
Tao, Ling
Mesenchymal Stromal Cells Overexpressing Farnesoid X Receptor Exert Cardioprotective Effects Against Acute Ischemic Heart Injury by Binding Endogenous Bile Acids (Adv. Sci. 24/2022)
title Mesenchymal Stromal Cells Overexpressing Farnesoid X Receptor Exert Cardioprotective Effects Against Acute Ischemic Heart Injury by Binding Endogenous Bile Acids (Adv. Sci. 24/2022)
title_full Mesenchymal Stromal Cells Overexpressing Farnesoid X Receptor Exert Cardioprotective Effects Against Acute Ischemic Heart Injury by Binding Endogenous Bile Acids (Adv. Sci. 24/2022)
title_fullStr Mesenchymal Stromal Cells Overexpressing Farnesoid X Receptor Exert Cardioprotective Effects Against Acute Ischemic Heart Injury by Binding Endogenous Bile Acids (Adv. Sci. 24/2022)
title_full_unstemmed Mesenchymal Stromal Cells Overexpressing Farnesoid X Receptor Exert Cardioprotective Effects Against Acute Ischemic Heart Injury by Binding Endogenous Bile Acids (Adv. Sci. 24/2022)
title_short Mesenchymal Stromal Cells Overexpressing Farnesoid X Receptor Exert Cardioprotective Effects Against Acute Ischemic Heart Injury by Binding Endogenous Bile Acids (Adv. Sci. 24/2022)
title_sort mesenchymal stromal cells overexpressing farnesoid x receptor exert cardioprotective effects against acute ischemic heart injury by binding endogenous bile acids (adv. sci. 24/2022)
topic Frontispiece
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462841/
http://dx.doi.org/10.1002/advs.202270152
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