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Advances in the Biology, Detection Techniques, and Clinical Applications of Circulating Tumor Cells
Circulating tumor cells (CTCs) play a crucial role in tumor recurrence and metastasis, and their early detection has shown remarkable benefits in clinical theranostics. However, CTCs are extremely rare, thus detecting them in the blood is very challenging. New CTC detection techniques are continuous...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462976/ https://www.ncbi.nlm.nih.gov/pubmed/36090904 http://dx.doi.org/10.1155/2022/7149686 |
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author | Wu, Siwen Zhao, Shubi Cui, Dawei Xie, Jue |
author_facet | Wu, Siwen Zhao, Shubi Cui, Dawei Xie, Jue |
author_sort | Wu, Siwen |
collection | PubMed |
description | Circulating tumor cells (CTCs) play a crucial role in tumor recurrence and metastasis, and their early detection has shown remarkable benefits in clinical theranostics. However, CTCs are extremely rare, thus detecting them in the blood is very challenging. New CTC detection techniques are continuously being developed, enabling deeper analysis of CTC biology and potential clinical application. This article reviews current CTC detection techniques and their clinical application. CTCs have provided, and will continue to provide, important insights into the process of metastasis, which could lead to development of new therapies for different cancers. |
format | Online Article Text |
id | pubmed-9462976 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-94629762022-09-10 Advances in the Biology, Detection Techniques, and Clinical Applications of Circulating Tumor Cells Wu, Siwen Zhao, Shubi Cui, Dawei Xie, Jue J Oncol Review Article Circulating tumor cells (CTCs) play a crucial role in tumor recurrence and metastasis, and their early detection has shown remarkable benefits in clinical theranostics. However, CTCs are extremely rare, thus detecting them in the blood is very challenging. New CTC detection techniques are continuously being developed, enabling deeper analysis of CTC biology and potential clinical application. This article reviews current CTC detection techniques and their clinical application. CTCs have provided, and will continue to provide, important insights into the process of metastasis, which could lead to development of new therapies for different cancers. Hindawi 2022-09-02 /pmc/articles/PMC9462976/ /pubmed/36090904 http://dx.doi.org/10.1155/2022/7149686 Text en Copyright © 2022 Siwen Wu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Wu, Siwen Zhao, Shubi Cui, Dawei Xie, Jue Advances in the Biology, Detection Techniques, and Clinical Applications of Circulating Tumor Cells |
title | Advances in the Biology, Detection Techniques, and Clinical Applications of Circulating Tumor Cells |
title_full | Advances in the Biology, Detection Techniques, and Clinical Applications of Circulating Tumor Cells |
title_fullStr | Advances in the Biology, Detection Techniques, and Clinical Applications of Circulating Tumor Cells |
title_full_unstemmed | Advances in the Biology, Detection Techniques, and Clinical Applications of Circulating Tumor Cells |
title_short | Advances in the Biology, Detection Techniques, and Clinical Applications of Circulating Tumor Cells |
title_sort | advances in the biology, detection techniques, and clinical applications of circulating tumor cells |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462976/ https://www.ncbi.nlm.nih.gov/pubmed/36090904 http://dx.doi.org/10.1155/2022/7149686 |
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