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Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols

In this study, the extended SEIR dynamical model is formulated to investigate the spread of coronavirus disease (COVID-19) via a special focus on contact with asymptomatic and self-isolated infected individuals. Furthermore, a mathematical analysis of the model, including positivity, boundedness, an...

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Detalles Bibliográficos
Autores principales: Shadi, Reza, Fakharian, Ahmad, Khaloozadeh, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462995/
https://www.ncbi.nlm.nih.gov/pubmed/36092782
http://dx.doi.org/10.1155/2022/7706447
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author Shadi, Reza
Fakharian, Ahmad
Khaloozadeh, Hamid
author_facet Shadi, Reza
Fakharian, Ahmad
Khaloozadeh, Hamid
author_sort Shadi, Reza
collection PubMed
description In this study, the extended SEIR dynamical model is formulated to investigate the spread of coronavirus disease (COVID-19) via a special focus on contact with asymptomatic and self-isolated infected individuals. Furthermore, a mathematical analysis of the model, including positivity, boundedness, and local and global stability of the disease-free and endemic equilibrium points in terms of the basic reproduction number, is presented. The sensitivity analysis indicates that reducing the disease contact rate and the transmissibility factor related to asymptomatic individuals, along with increasing the quarantine/self-isolation rate and the contact-tracing process, from the view of flattening the curve for novel coronavirus, are crucial to the reduction in disease-related deaths.
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spelling pubmed-94629952022-09-10 Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols Shadi, Reza Fakharian, Ahmad Khaloozadeh, Hamid Comput Math Methods Med Research Article In this study, the extended SEIR dynamical model is formulated to investigate the spread of coronavirus disease (COVID-19) via a special focus on contact with asymptomatic and self-isolated infected individuals. Furthermore, a mathematical analysis of the model, including positivity, boundedness, and local and global stability of the disease-free and endemic equilibrium points in terms of the basic reproduction number, is presented. The sensitivity analysis indicates that reducing the disease contact rate and the transmissibility factor related to asymptomatic individuals, along with increasing the quarantine/self-isolation rate and the contact-tracing process, from the view of flattening the curve for novel coronavirus, are crucial to the reduction in disease-related deaths. Hindawi 2022-09-02 /pmc/articles/PMC9462995/ /pubmed/36092782 http://dx.doi.org/10.1155/2022/7706447 Text en Copyright © 2022 Reza Shadi et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Shadi, Reza
Fakharian, Ahmad
Khaloozadeh, Hamid
Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols
title Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols
title_full Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols
title_fullStr Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols
title_full_unstemmed Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols
title_short Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols
title_sort modeling and analysis of covid-19 spread: the impacts of nonpharmaceutical protocols
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462995/
https://www.ncbi.nlm.nih.gov/pubmed/36092782
http://dx.doi.org/10.1155/2022/7706447
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