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Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols
In this study, the extended SEIR dynamical model is formulated to investigate the spread of coronavirus disease (COVID-19) via a special focus on contact with asymptomatic and self-isolated infected individuals. Furthermore, a mathematical analysis of the model, including positivity, boundedness, an...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462995/ https://www.ncbi.nlm.nih.gov/pubmed/36092782 http://dx.doi.org/10.1155/2022/7706447 |
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author | Shadi, Reza Fakharian, Ahmad Khaloozadeh, Hamid |
author_facet | Shadi, Reza Fakharian, Ahmad Khaloozadeh, Hamid |
author_sort | Shadi, Reza |
collection | PubMed |
description | In this study, the extended SEIR dynamical model is formulated to investigate the spread of coronavirus disease (COVID-19) via a special focus on contact with asymptomatic and self-isolated infected individuals. Furthermore, a mathematical analysis of the model, including positivity, boundedness, and local and global stability of the disease-free and endemic equilibrium points in terms of the basic reproduction number, is presented. The sensitivity analysis indicates that reducing the disease contact rate and the transmissibility factor related to asymptomatic individuals, along with increasing the quarantine/self-isolation rate and the contact-tracing process, from the view of flattening the curve for novel coronavirus, are crucial to the reduction in disease-related deaths. |
format | Online Article Text |
id | pubmed-9462995 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-94629952022-09-10 Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols Shadi, Reza Fakharian, Ahmad Khaloozadeh, Hamid Comput Math Methods Med Research Article In this study, the extended SEIR dynamical model is formulated to investigate the spread of coronavirus disease (COVID-19) via a special focus on contact with asymptomatic and self-isolated infected individuals. Furthermore, a mathematical analysis of the model, including positivity, boundedness, and local and global stability of the disease-free and endemic equilibrium points in terms of the basic reproduction number, is presented. The sensitivity analysis indicates that reducing the disease contact rate and the transmissibility factor related to asymptomatic individuals, along with increasing the quarantine/self-isolation rate and the contact-tracing process, from the view of flattening the curve for novel coronavirus, are crucial to the reduction in disease-related deaths. Hindawi 2022-09-02 /pmc/articles/PMC9462995/ /pubmed/36092782 http://dx.doi.org/10.1155/2022/7706447 Text en Copyright © 2022 Reza Shadi et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Shadi, Reza Fakharian, Ahmad Khaloozadeh, Hamid Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols |
title | Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols |
title_full | Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols |
title_fullStr | Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols |
title_full_unstemmed | Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols |
title_short | Modeling and Analysis of COVID-19 Spread: The Impacts of Nonpharmaceutical Protocols |
title_sort | modeling and analysis of covid-19 spread: the impacts of nonpharmaceutical protocols |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462995/ https://www.ncbi.nlm.nih.gov/pubmed/36092782 http://dx.doi.org/10.1155/2022/7706447 |
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