Cargando…
Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants
We designed a protein biosensor that uses thermodynamic coupling for sensitive and rapid detection of neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants in serum. The biosensor is a switchable, caged luciferase–receptor-binding domain (RBD) construc...
Autores principales: | Zhang, Jason Z., Yeh, Hsien-Wei, Walls, Alexandra C., Wicky, Basile I. M., Sprouse, Kaitlin R., VanBlargan, Laura A., Treger, Rebecca, Quijano-Rubio, Alfredo, Pham, Minh N., Kraft, John C., Haydon, Ian C., Yang, Wei, DeWitt, Michelle, Bowen, John E., Chow, Cameron M., Carter, Lauren, Ravichandran, Rashmi, Wener, Mark H., Stewart, Lance, Veesler, David, Diamond, Michael S., Greninger, Alexander L., Koelle, David M., Baker, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463068/ https://www.ncbi.nlm.nih.gov/pubmed/35484405 http://dx.doi.org/10.1038/s41587-022-01280-8 |
Ejemplares similares
-
A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis
por: Goo, Leslie, et al.
Publicado: (2017) -
Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice
por: Walls, Alexandra C., et al.
Publicado: (2022) -
Delta breakthrough infections elicit potent, broad and durable neutralizing antibody responses
por: Walls, Alexandra C., et al.
Publicado: (2021) -
An mRNA Vaccine Protects Mice against Multiple Tick-Transmitted Flavivirus Infections
por: VanBlargan, Laura A., et al.
Publicado: (2018) -
SARS-CoV-2 breakthrough infections elicit potent, broad, and durable neutralizing antibody responses
por: Walls, Alexandra C., et al.
Publicado: (2022)