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Human lung-resident mucosal-associated invariant T cells are abundant, express antimicrobial proteins, and are cytokine responsive

Mucosal-associated Invariant T (MAIT) cells are an innate-like T cell subset that recognize a broad array of microbial pathogens, including respiratory pathogens. Here we investigate the transcriptional profile of MAIT cells localized to the human lung, and postulate that MAIT cells may play a role...

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Detalles Bibliográficos
Autores principales: Meermeier, Erin W., Zheng, Christina L., Tran, Jessica G., Soma, Shogo, Worley, Aneta H., Weiss, David I., Modlin, Robert L., Swarbrick, Gwendolyn, Karamooz, Elham, Khuzwayo, Sharon, Wong, Emily B., Gold, Marielle C., Lewinsohn, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463188/
https://www.ncbi.nlm.nih.gov/pubmed/36085311
http://dx.doi.org/10.1038/s42003-022-03823-w