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Pharmacological Modulation of Glutamatergic and Neuroinflammatory Pathways in a Lafora Disease Mouse Model

Lafora disease (LD) is a fatal rare neurodegenerative disorder that affects young adolescents and has no treatment yet. The hallmark of LD is the presence of polyglucosan inclusions (PGs), called Lafora bodies (LBs), in the brain and peripheral tissues. LD is caused by mutations in either EPM2A or E...

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Detalles Bibliográficos
Autores principales: Mollá, Belén, Heredia, Miguel, Campos, Ángela, Sanz, Pascual
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463199/
https://www.ncbi.nlm.nih.gov/pubmed/35835895
http://dx.doi.org/10.1007/s12035-022-02956-7