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SCFAs Ameliorate Chronic Postsurgical Pain–Related Cognition Dysfunction via the ACSS2-HDAC2 Axis in Rats

Patients with chronic postsurgical pain (CPSP) frequently exhibit comorbid cognitive deficits. Recent observations have emphasized the critical effects of gut microbial metabolites, like short-chain fatty acids (SCFAs), in regulating cognitive function. However, the underlying mechanisms and effecti...

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Detalles Bibliográficos
Autores principales:	Li, Zhen, Sun, Tianning, He, Zhigang, Li, Zhixiao, Zhang, Wencui, Wang, Jie, Xiang, Hongbing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463230/ https://www.ncbi.nlm.nih.gov/pubmed/35902549 http://dx.doi.org/10.1007/s12035-022-02971-8

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