Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M — a case report

Since high grade gliomas are aggressive brain tumors, intensive search for new treatment options is ongoing. For adult patients with newly diagnosed (ndGBM) and recurrent glioblastoma (rGBM), low intensity intermediate frequency alternating electric fields, known as tumor treating fields (TTFields)...

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Autores principales: Gött, Hanna, Kiez, Silke, Dohmen, Hildegard, Kolodziej, Malgorzata, Stein, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463302/
https://www.ncbi.nlm.nih.gov/pubmed/35181800
http://dx.doi.org/10.1007/s00381-022-05465-z
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author Gött, Hanna
Kiez, Silke
Dohmen, Hildegard
Kolodziej, Malgorzata
Stein, Marco
author_facet Gött, Hanna
Kiez, Silke
Dohmen, Hildegard
Kolodziej, Malgorzata
Stein, Marco
author_sort Gött, Hanna
collection PubMed
description Since high grade gliomas are aggressive brain tumors, intensive search for new treatment options is ongoing. For adult patients with newly diagnosed (ndGBM) and recurrent glioblastoma (rGBM), low intensity intermediate frequency alternating electric fields, known as tumor treating fields (TTFields) have been established as a new treatment modality. Tumor treating fields significantly increase survival rates in combination with adjuvant temozolomide (TMZ) in adult and GBM patients. Here, we report about feasibility and safety of treatment on a pediatric patient with diffuse midline glioma who is receiving TTFields therapy in combination with temozolomide.
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spelling pubmed-94633022022-09-11 Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M — a case report Gött, Hanna Kiez, Silke Dohmen, Hildegard Kolodziej, Malgorzata Stein, Marco Childs Nerv Syst Case Report Since high grade gliomas are aggressive brain tumors, intensive search for new treatment options is ongoing. For adult patients with newly diagnosed (ndGBM) and recurrent glioblastoma (rGBM), low intensity intermediate frequency alternating electric fields, known as tumor treating fields (TTFields) have been established as a new treatment modality. Tumor treating fields significantly increase survival rates in combination with adjuvant temozolomide (TMZ) in adult and GBM patients. Here, we report about feasibility and safety of treatment on a pediatric patient with diffuse midline glioma who is receiving TTFields therapy in combination with temozolomide. Springer Berlin Heidelberg 2022-02-18 2022 /pmc/articles/PMC9463302/ /pubmed/35181800 http://dx.doi.org/10.1007/s00381-022-05465-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Case Report
Gött, Hanna
Kiez, Silke
Dohmen, Hildegard
Kolodziej, Malgorzata
Stein, Marco
Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M — a case report
title Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M — a case report
title_full Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M — a case report
title_fullStr Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M — a case report
title_full_unstemmed Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M — a case report
title_short Tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma H3K27M — a case report
title_sort tumor treating fields therapy is feasible and safe in a 3-year-old patient with diffuse midline glioma h3k27m — a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463302/
https://www.ncbi.nlm.nih.gov/pubmed/35181800
http://dx.doi.org/10.1007/s00381-022-05465-z
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