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A phase II study of retifanlimab (INCMGA00012) in patients with squamous carcinoma of the anal canal who have progressed following platinum-based chemotherapy (POD1UM-202)
BACKGROUND: Locally advanced or metastatic squamous carcinoma of the anal canal (SCAC) has poor prognosis following platinum-based chemotherapy. Retifanlimab (INCMGA00012), a humanized monoclonal antibody targeting programmed death protein-1 (PD-1), demonstrated clinical activity across a range of s...
Autores principales: | Rao, S., Anandappa, G., Capdevila, J., Dahan, L., Evesque, L., Kim, S., Saunders, M.P., Gilbert, D.C., Jensen, L.H., Samalin, E., Spindler, K.-L., Tamberi, S., Demols, A., Guren, M.G., Arnold, D., Fakih, M., Kayyal, T., Cornfeld, M., Tian, C., Catlett, M., Smith, M., Spano, J.-P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463376/ https://www.ncbi.nlm.nih.gov/pubmed/35816951 http://dx.doi.org/10.1016/j.esmoop.2022.100529 |
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