In vivo tumor immune microenvironment phenotypes correlate with inflammation and vasculature to predict immunotherapy response

Response to immunotherapies can be variable and unpredictable. Pathology-based phenotyping of tumors into ‘hot’ and ‘cold’ is static, relying solely on T-cell infiltration in single-time single-site biopsies, resulting in suboptimal treatment response prediction. Dynamic vascular events (tumor angio...

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Detalles Bibliográficos
Autores principales: Sahu, Aditi, Kose, Kivanc, Kraehenbuehl, Lukas, Byers, Candice, Holland, Aliya, Tembo, Teguru, Santella, Anthony, Alfonso, Anabel, Li, Madison, Cordova, Miguel, Gill, Melissa, Fox, Christi, Gonzalez, Salvador, Kumar, Piyush, Wang, Amber Weiching, Kurtansky, Nicholas, Chandrani, Pratik, Yin, Shen, Mehta, Paras, Navarrete-Dechent, Cristian, Peterson, Gary, King, Kimeil, Dusza, Stephen, Yang, Ning, Liu, Shuaitong, Phillips, William, Guitera, Pascale, Rossi, Anthony, Halpern, Allan, Deng, Liang, Pulitzer, Melissa, Marghoob, Ashfaq, Chen, Chih-Shan Jason, Merghoub, Taha, Rajadhyaksha, Milind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463451/
https://www.ncbi.nlm.nih.gov/pubmed/36085288
http://dx.doi.org/10.1038/s41467-022-32738-7

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