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MicroRNA-dependent inhibition of WEE1 controls cancer stem-like characteristics and malignant behavior in ovarian cancer

Cancer stem-like cells (CSCs) have been suggested to be responsible for chemoresistance and tumor recurrence owing to their self-renewal capacity and differentiation potential. Although WEE1 is a strong candidate target for anticancer therapies, its role in ovarian CSCs is yet to be elucidated. Here...

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Detalles Bibliográficos
Autores principales: Cho, Jin Gu, Kim, Sung-wook, Lee, Aram, Jeong, Ha-neul, Yun, Eunsik, Choi, Jihea, Jeong, Su Jin, Chang, Woochul, Oh, Sumin, Yoo, Kyung Hyun, Lee, Jung Bok, Yoon, Sukjoon, Lee, Myeong-Sok, Park, Jong Hoon, Jung, Min Hyung, Kim, So-Woon, Kim, Ki Hyung, Suh, Dong Soo, Choi, Kyung Un, Choi, Jungmin, Kim, Jongmin, Kwon, Byung Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463562/
https://www.ncbi.nlm.nih.gov/pubmed/36159587
http://dx.doi.org/10.1016/j.omtn.2022.08.028