Cyclophosphamide depletes tumor infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma

The outcome for children with high-risk neuroblastoma is poor despite intensive multi-modal treatment protocols. Toxicity from current treatments is significant, and novel approaches are needed to improve outcome. Cyclophosphamide (CPM) is a key component of current chemotherapy regimens and is know...

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Detalles Bibliográficos
Autores principales: Webb, Emily R., Moreno-Vincente, Julia, Easton, Alistair, Lanati, Silvia, Taylor, Martin, James, Sonya, Williams, Emily L., English, Vikki, Penfold, Chris, Beers, Stephen A., Gray, Juliet C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463572/
https://www.ncbi.nlm.nih.gov/pubmed/36097618
http://dx.doi.org/10.1016/j.isci.2022.104995

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