Enhanced production of amyrin in Yarrowia lipolytica using a combinatorial protein and metabolic engineering approach

BACKGROUND: Amyrin is an important triterpenoid and precursor to a wide range of cosmetic, pharmaceutical and nutraceutical products. In this study, we metabolically engineered the oleaginous yeast, Yarrowia lipolytica to produce α- and β-amyrin on simple sugar and waste cooking oil. RESULTS: We fir...

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Detalles Bibliográficos
Autores principales: Kong, Jing, Miao, Lin, Lu, Zhihui, Wang, Shuhui, Zhao, Baixiang, Zhang, Cuiying, Xiao, Dongguang, Teo, Desmond, Leong, Susanna Su Jan, Wong, Adison, Yu, Aiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463779/
https://www.ncbi.nlm.nih.gov/pubmed/36085205
http://dx.doi.org/10.1186/s12934-022-01915-0

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