Seroprevalence of anti‐myelin oligodendrocyte glycoprotein antibodies in adults with myelitis

Although myelitis is the second most common presentation in adults with myelin oligodendrocyte glycoprotein (MOG) antibody‐associated disease (MOGAD), studies on MOG‐IgG seroprevalence in patients with myelitis episodes are sparse. Herein, we investigated MOG‐IgG seroprevalence in Korean adults who...

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Autores principales: Kim, Ki Hoon, Kim, Su‐Hyun, Hyun, Jae‐Won, Kim, Yeseul, Park, Hyewon, Kim, Ho Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463949/
https://www.ncbi.nlm.nih.gov/pubmed/35932473
http://dx.doi.org/10.1002/acn3.51642
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author Kim, Ki Hoon
Kim, Su‐Hyun
Hyun, Jae‐Won
Kim, Yeseul
Park, Hyewon
Kim, Ho Jin
author_facet Kim, Ki Hoon
Kim, Su‐Hyun
Hyun, Jae‐Won
Kim, Yeseul
Park, Hyewon
Kim, Ho Jin
author_sort Kim, Ki Hoon
collection PubMed
description Although myelitis is the second most common presentation in adults with myelin oligodendrocyte glycoprotein (MOG) antibody‐associated disease (MOGAD), studies on MOG‐IgG seroprevalence in patients with myelitis episodes are sparse. Herein, we investigated MOG‐IgG seroprevalence in Korean adults who exhibited myelitis since 2017. Among 151 adults with acute myelitis, 11 (7.3%) tested positive for MOG‐IgG by the initial screening and 10 (6.6%) patients were finally diagnosed with MOGAD during the study period. This study is the first to provide data on MOG‐IgG seroprevalence in adults with myelitis and supports the clinical utility and importance of MOG‐IgG testing in myelitis episodes.
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spelling pubmed-94639492022-09-13 Seroprevalence of anti‐myelin oligodendrocyte glycoprotein antibodies in adults with myelitis Kim, Ki Hoon Kim, Su‐Hyun Hyun, Jae‐Won Kim, Yeseul Park, Hyewon Kim, Ho Jin Ann Clin Transl Neurol Brief Communications Although myelitis is the second most common presentation in adults with myelin oligodendrocyte glycoprotein (MOG) antibody‐associated disease (MOGAD), studies on MOG‐IgG seroprevalence in patients with myelitis episodes are sparse. Herein, we investigated MOG‐IgG seroprevalence in Korean adults who exhibited myelitis since 2017. Among 151 adults with acute myelitis, 11 (7.3%) tested positive for MOG‐IgG by the initial screening and 10 (6.6%) patients were finally diagnosed with MOGAD during the study period. This study is the first to provide data on MOG‐IgG seroprevalence in adults with myelitis and supports the clinical utility and importance of MOG‐IgG testing in myelitis episodes. John Wiley and Sons Inc. 2022-08-06 /pmc/articles/PMC9463949/ /pubmed/35932473 http://dx.doi.org/10.1002/acn3.51642 Text en © 2022 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Brief Communications
Kim, Ki Hoon
Kim, Su‐Hyun
Hyun, Jae‐Won
Kim, Yeseul
Park, Hyewon
Kim, Ho Jin
Seroprevalence of anti‐myelin oligodendrocyte glycoprotein antibodies in adults with myelitis
title Seroprevalence of anti‐myelin oligodendrocyte glycoprotein antibodies in adults with myelitis
title_full Seroprevalence of anti‐myelin oligodendrocyte glycoprotein antibodies in adults with myelitis
title_fullStr Seroprevalence of anti‐myelin oligodendrocyte glycoprotein antibodies in adults with myelitis
title_full_unstemmed Seroprevalence of anti‐myelin oligodendrocyte glycoprotein antibodies in adults with myelitis
title_short Seroprevalence of anti‐myelin oligodendrocyte glycoprotein antibodies in adults with myelitis
title_sort seroprevalence of anti‐myelin oligodendrocyte glycoprotein antibodies in adults with myelitis
topic Brief Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463949/
https://www.ncbi.nlm.nih.gov/pubmed/35932473
http://dx.doi.org/10.1002/acn3.51642
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