Reconstitution of monoterpene indole alkaloid biosynthesis in genome engineered Nicotiana benthamiana

Monoterpene indole alkaloids (MIAs) are a diverse class of plant natural products that include a number of medicinally important compounds. We set out to reconstitute the pathway for strictosidine, a key intermediate of all MIAs, from central metabolism in Nicotiana benthamiana. A disadvantage of th...

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Detalles Bibliográficos
Autores principales: Dudley, Quentin M., Jo, Seohyun, Guerrero, Delia Ayled Serna, Chhetry, Monika, Smedley, Mark A., Harwood, Wendy A., Sherden, Nathaniel H., O’Connor, Sarah E., Caputi, Lorenzo, Patron, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464250/
https://www.ncbi.nlm.nih.gov/pubmed/36088516
http://dx.doi.org/10.1038/s42003-022-03904-w

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