Genomic and Metabolic Hallmarks of SDH- and FH-deficient Renal Cell Carcinomas

BACKGROUND: Succinate dehydrogenase-deficient and fumarate hydratase-deficient renal cell carcinomas (SDHRCC and FHRCC) are rare kidney cancers driven by loss of TCA cycle enzymes. OBJECTIVE: To define and compare the genomic and metabolomic hallmarks of SDHRCC and FHRCC. DESIGN, SETTING, AND PARTIC...

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Detalles Bibliográficos
Autores principales: Yoo, Angela, Tang, Cerise, Zucker, Mark, Fitzgerald, Kelly, DiNatale, Renzo G., Rappold, Phillip M., Weiss, Kate, Freeman, Benjamin, Lee, Chung-Han, Schultz, Nikolaus, Motzer, Robert, Russo, Paul, Coleman, Jonathan, Reuter, Victor E., Chen, Ying-Bei, Carlo, Maria I., Gill, Anthony J., Kotecha, Ritesh R., Hakimi, A. Ari, Reznik, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464266/
https://www.ncbi.nlm.nih.gov/pubmed/35288096
http://dx.doi.org/10.1016/j.euf.2021.12.002

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