S-nitroso-L-cysteine stereoselectively blunts the adverse effects of morphine on breathing and arterial blood gas chemistry while promoting analgesia

S-nitrosothiols exert multiple effects on neural processes in the central and peripheral nervous system. This study shows that intravenous infusion of S-nitroso-L-cysteine (SNO-L-CYS, 1 μmol/kg/min) in anesthetized male Sprague Dawley rats elicits (a) sustained increases in minute ventilation, via i...

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Detalles Bibliográficos
Autores principales: Getsy, Paulina M., Young, Alex P., Bates, James N., Baby, Santhosh M., Seckler, James M., Grossfield, Alan, Hsieh, Yee-Hsee, Lewis, Tristan H.J., Jenkins, Michael W., Gaston, Benjamin, Lewis, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464305/
https://www.ncbi.nlm.nih.gov/pubmed/36076552
http://dx.doi.org/10.1016/j.biopha.2022.113436

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