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QKI degradation in macrophage by RNF6 protects mice from MRSA infection via enhancing PI3K p110β dependent autophagy

BACKGROUND: Sepsis is a fatal condition commonly caused by Methicillin-resistant Staphylococcus aureus (MRSA) with a high death rate. Macrophages can protect the host from various microbial pathogens by recognizing and eliminating them. Earlier we found that Quaking (QKI), an RNA binding protein (RB...

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Detalles Bibliográficos
Autores principales:	Zhai, Dongsheng, Wang, Wenwen, Ye, Zichen, Xue, Ke, Chen, Guo, Hu, Sijun, Yan, Zhao, Guo, Yanhai, Wang, Fang, Li, Xubo, Xiang, An, Li, Xia, Lu, Zifan, Wang, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464412/ https://www.ncbi.nlm.nih.gov/pubmed/36088389 http://dx.doi.org/10.1186/s13578-022-00865-9

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