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In silico prediction, characterization, docking studies and molecular dynamics simulation of human p97 in complex with p37 cofactor

BACKGROUND: The AAA + ATPase p97 is an essential unfoldase/segragase involved in a multitude of cellular processes. It functions as a molecular machine critical for protein homeostasis, homotypic membrane fusion events and organelle biogenesis during mitosis in which it acts in concert with cofactor...

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Detalles Bibliográficos
Autores principales: Mirzadeh, Abolfazl, Kobakhidze, George, Vuillemot, Rémi, Jonic, Slavica, Rouiller, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464413/
https://www.ncbi.nlm.nih.gov/pubmed/36088301
http://dx.doi.org/10.1186/s12860-022-00437-2