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In silico prediction, characterization, docking studies and molecular dynamics simulation of human p97 in complex with p37 cofactor
BACKGROUND: The AAA + ATPase p97 is an essential unfoldase/segragase involved in a multitude of cellular processes. It functions as a molecular machine critical for protein homeostasis, homotypic membrane fusion events and organelle biogenesis during mitosis in which it acts in concert with cofactor...
Autores principales: | Mirzadeh, Abolfazl, Kobakhidze, George, Vuillemot, Rémi, Jonic, Slavica, Rouiller, Isabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464413/ https://www.ncbi.nlm.nih.gov/pubmed/36088301 http://dx.doi.org/10.1186/s12860-022-00437-2 |
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