Study protocol for a randomised controlled trial of diacerein versus placebo to treat knee osteoarthritis with effusion-synovitis (DICKENS)

BACKGROUND: There is an unmet need for treatments for knee osteoarthritis (OA). Effusion-synovitis is a common inflammatory phenotype of knee OA and predicts knee pain and structural degradation. Anti-inflammatory therapies, such as diacerein, may be effective for this phenotype. While diacerein is...

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Detalles Bibliográficos
Autores principales: Cai, Guoqi, Jones, Graeme, Cicuttini, Flavia M., Wluka, Anita E., Wang, Yuanyuan, Hill, Catherine, Keen, Helen, Antony, Benny, Wang, Xia, de Graaff, Barbara, Thompson, Michael, Winzenberg, Tania, Buttigieg, Kathy, Aitken, Dawn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464426/
https://www.ncbi.nlm.nih.gov/pubmed/36089595
http://dx.doi.org/10.1186/s13063-022-06715-w

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