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Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature

Struma ovarii is a rare variety of specialized monodermal mature ovarian teratoma, it is composed predominantly of thyroid tissue. Ascites is present in one third of patients. The combination of struma ovarii, marked ascites and elevated CA125 is a rare condition, which may mimic ovarian cancer. We...

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Autores principales: Wang, Shaoyu, He, Xinqin, Yang, Huijuan, Chen, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464449/
https://www.ncbi.nlm.nih.gov/pubmed/36101557
http://dx.doi.org/10.2147/IJWH.S379128
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author Wang, Shaoyu
He, Xinqin
Yang, Huijuan
Chen, Lihong
author_facet Wang, Shaoyu
He, Xinqin
Yang, Huijuan
Chen, Lihong
author_sort Wang, Shaoyu
collection PubMed
description Struma ovarii is a rare variety of specialized monodermal mature ovarian teratoma, it is composed predominantly of thyroid tissue. Ascites is present in one third of patients. The combination of struma ovarii, marked ascites and elevated CA125 is a rare condition, which may mimic ovarian cancer. We described two cases presenting with pelvic mass, ascites and elevated serum CA125 levels, frozen section and final pathology turned out to be struma ovarii. Ascites disappeared and the level of CA125 returned to normal level after operation. One of the cases was associated with pleural effusion, leading to a condition called pseudo-Meigs’ syndrome. Then we reviewed the related literatures to explore the possible mechanism of ascites and pleural effusion, the reason of CA125 elevation and imaging manifestations of struma ovarii. In conclusion, struma ovarii should be considered in the differential diagnosis preoperatively, when presented with pelvic mass, ascites and an elevated CA125 level.
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spelling pubmed-94644492022-09-12 Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature Wang, Shaoyu He, Xinqin Yang, Huijuan Chen, Lihong Int J Womens Health Case Series Struma ovarii is a rare variety of specialized monodermal mature ovarian teratoma, it is composed predominantly of thyroid tissue. Ascites is present in one third of patients. The combination of struma ovarii, marked ascites and elevated CA125 is a rare condition, which may mimic ovarian cancer. We described two cases presenting with pelvic mass, ascites and elevated serum CA125 levels, frozen section and final pathology turned out to be struma ovarii. Ascites disappeared and the level of CA125 returned to normal level after operation. One of the cases was associated with pleural effusion, leading to a condition called pseudo-Meigs’ syndrome. Then we reviewed the related literatures to explore the possible mechanism of ascites and pleural effusion, the reason of CA125 elevation and imaging manifestations of struma ovarii. In conclusion, struma ovarii should be considered in the differential diagnosis preoperatively, when presented with pelvic mass, ascites and an elevated CA125 level. Dove 2022-09-07 /pmc/articles/PMC9464449/ /pubmed/36101557 http://dx.doi.org/10.2147/IJWH.S379128 Text en © 2022 Wang et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Series
Wang, Shaoyu
He, Xinqin
Yang, Huijuan
Chen, Lihong
Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature
title Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature
title_full Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature
title_fullStr Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature
title_full_unstemmed Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature
title_short Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature
title_sort struma ovarii associated with ascites and elevated ca125: two case reports and review of the literature
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464449/
https://www.ncbi.nlm.nih.gov/pubmed/36101557
http://dx.doi.org/10.2147/IJWH.S379128
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