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Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature
Struma ovarii is a rare variety of specialized monodermal mature ovarian teratoma, it is composed predominantly of thyroid tissue. Ascites is present in one third of patients. The combination of struma ovarii, marked ascites and elevated CA125 is a rare condition, which may mimic ovarian cancer. We...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464449/ https://www.ncbi.nlm.nih.gov/pubmed/36101557 http://dx.doi.org/10.2147/IJWH.S379128 |
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author | Wang, Shaoyu He, Xinqin Yang, Huijuan Chen, Lihong |
author_facet | Wang, Shaoyu He, Xinqin Yang, Huijuan Chen, Lihong |
author_sort | Wang, Shaoyu |
collection | PubMed |
description | Struma ovarii is a rare variety of specialized monodermal mature ovarian teratoma, it is composed predominantly of thyroid tissue. Ascites is present in one third of patients. The combination of struma ovarii, marked ascites and elevated CA125 is a rare condition, which may mimic ovarian cancer. We described two cases presenting with pelvic mass, ascites and elevated serum CA125 levels, frozen section and final pathology turned out to be struma ovarii. Ascites disappeared and the level of CA125 returned to normal level after operation. One of the cases was associated with pleural effusion, leading to a condition called pseudo-Meigs’ syndrome. Then we reviewed the related literatures to explore the possible mechanism of ascites and pleural effusion, the reason of CA125 elevation and imaging manifestations of struma ovarii. In conclusion, struma ovarii should be considered in the differential diagnosis preoperatively, when presented with pelvic mass, ascites and an elevated CA125 level. |
format | Online Article Text |
id | pubmed-9464449 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-94644492022-09-12 Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature Wang, Shaoyu He, Xinqin Yang, Huijuan Chen, Lihong Int J Womens Health Case Series Struma ovarii is a rare variety of specialized monodermal mature ovarian teratoma, it is composed predominantly of thyroid tissue. Ascites is present in one third of patients. The combination of struma ovarii, marked ascites and elevated CA125 is a rare condition, which may mimic ovarian cancer. We described two cases presenting with pelvic mass, ascites and elevated serum CA125 levels, frozen section and final pathology turned out to be struma ovarii. Ascites disappeared and the level of CA125 returned to normal level after operation. One of the cases was associated with pleural effusion, leading to a condition called pseudo-Meigs’ syndrome. Then we reviewed the related literatures to explore the possible mechanism of ascites and pleural effusion, the reason of CA125 elevation and imaging manifestations of struma ovarii. In conclusion, struma ovarii should be considered in the differential diagnosis preoperatively, when presented with pelvic mass, ascites and an elevated CA125 level. Dove 2022-09-07 /pmc/articles/PMC9464449/ /pubmed/36101557 http://dx.doi.org/10.2147/IJWH.S379128 Text en © 2022 Wang et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Case Series Wang, Shaoyu He, Xinqin Yang, Huijuan Chen, Lihong Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature |
title | Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature |
title_full | Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature |
title_fullStr | Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature |
title_full_unstemmed | Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature |
title_short | Struma Ovarii Associated with Ascites and Elevated CA125: Two Case Reports and Review of the Literature |
title_sort | struma ovarii associated with ascites and elevated ca125: two case reports and review of the literature |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464449/ https://www.ncbi.nlm.nih.gov/pubmed/36101557 http://dx.doi.org/10.2147/IJWH.S379128 |
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