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IL-13 Regulates Orai1 Expression in Human Bronchial Smooth Muscle Cells and Airway Remodeling in Asthma Mice Model via LncRNA H19

BACKGROUND: Increased proliferation and hypertrophy of airway smooth muscle cells (ASMCs) contribute substantially to airway remodeling in asthma. Interleukin (IL)-13 regulates ASMC proliferation by increasing Orai1 expression, the pore-forming subunit of store-operated Ca(2+) entry (SOCE). The unde...

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Detalles Bibliográficos
Autores principales:	Xiang, Lin-Li, Wan, Qian-Qian, Wang, Yi-Min, He, Shao-Jun, Xu, Wen-Juan, Ding, Mei, Zhang, Jin-Jin, Sun, Yuan-Li, Dong, Xiang, Zhou, Ying, Cui, Yu-Bao, Gao, Ya-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464454/ https://www.ncbi.nlm.nih.gov/pubmed/36101840 http://dx.doi.org/10.2147/JAA.S360381

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