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Dermoscopic Evaluation of Extragenital Lichen Sclerosus et Atrophicus
INTRODUCTION: Lichen sclerosus (LS), is an uncommon inflammatory dermatosis with preferential involvement of anogenital region. Diagnosis of LS is mainly clinical, but clinical differentiation from conditions like vitiligo, morphea may be a difficult task at times that often requires histological an...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mattioli 1885
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464556/ https://www.ncbi.nlm.nih.gov/pubmed/36159134 http://dx.doi.org/10.5826/dpc.1203a125 |
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author | Mahajan, Sunanda Arun Dave, Jayati Shailesh |
author_facet | Mahajan, Sunanda Arun Dave, Jayati Shailesh |
author_sort | Mahajan, Sunanda Arun |
collection | PubMed |
description | INTRODUCTION: Lichen sclerosus (LS), is an uncommon inflammatory dermatosis with preferential involvement of anogenital region. Diagnosis of LS is mainly clinical, but clinical differentiation from conditions like vitiligo, morphea may be a difficult task at times that often requires histological analysis. Dermoscopy is one such non-invasive tool which can help diagnose the disease. There is paucity of Indian data on dermoscopy of LS. OBJECTIVES: To evaluate clinical, dermatoscopic patterns of LS and correlate them with histopathology. METHODS: The study was conducted in a tertiary hospital after obtaining consent from 20 patients. OITEZ e-scope digital microscope was used to evaluate the lesions. Both polarized and nonpolarized mode were used and skin biopsy was done to confirm diagnosis. RESULTS: Based on morphology, LS was classified as scleroatrophic lesions (61.5%), guttate lesions (30.8%) and hyperkeratotic lesions (7.7%). Dermoscopic analysis revealed structureless white to yellow areas as most common finding (100%) followed by chrysalis like structure (80.8%). Linear irregular vessels were seen in 61.5% lesions and perifollicular scaling in 50.0% lesions. Keratotic plugs were seen in 50.0% lesions. A new characteristic finding, “rosettes” was seen in 38.5% lesions has never been reported with LS before. Non polarized mode was particularly useful for identifying texture changes, keratotic plugs and minute scales which were not visible otherwise. CONCLUSIONS: Dermoscopy is a simple diagnostic tool that helps in the early diagnosis of LS with specific pattern which can avoid invasive procedure like biopsy. Both non-polarised and polarized dermoscopy must be done to visualize the changes of LS well. |
format | Online Article Text |
id | pubmed-9464556 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Mattioli 1885 |
record_format | MEDLINE/PubMed |
spelling | pubmed-94645562022-09-23 Dermoscopic Evaluation of Extragenital Lichen Sclerosus et Atrophicus Mahajan, Sunanda Arun Dave, Jayati Shailesh Dermatol Pract Concept Original Article INTRODUCTION: Lichen sclerosus (LS), is an uncommon inflammatory dermatosis with preferential involvement of anogenital region. Diagnosis of LS is mainly clinical, but clinical differentiation from conditions like vitiligo, morphea may be a difficult task at times that often requires histological analysis. Dermoscopy is one such non-invasive tool which can help diagnose the disease. There is paucity of Indian data on dermoscopy of LS. OBJECTIVES: To evaluate clinical, dermatoscopic patterns of LS and correlate them with histopathology. METHODS: The study was conducted in a tertiary hospital after obtaining consent from 20 patients. OITEZ e-scope digital microscope was used to evaluate the lesions. Both polarized and nonpolarized mode were used and skin biopsy was done to confirm diagnosis. RESULTS: Based on morphology, LS was classified as scleroatrophic lesions (61.5%), guttate lesions (30.8%) and hyperkeratotic lesions (7.7%). Dermoscopic analysis revealed structureless white to yellow areas as most common finding (100%) followed by chrysalis like structure (80.8%). Linear irregular vessels were seen in 61.5% lesions and perifollicular scaling in 50.0% lesions. Keratotic plugs were seen in 50.0% lesions. A new characteristic finding, “rosettes” was seen in 38.5% lesions has never been reported with LS before. Non polarized mode was particularly useful for identifying texture changes, keratotic plugs and minute scales which were not visible otherwise. CONCLUSIONS: Dermoscopy is a simple diagnostic tool that helps in the early diagnosis of LS with specific pattern which can avoid invasive procedure like biopsy. Both non-polarised and polarized dermoscopy must be done to visualize the changes of LS well. Mattioli 1885 2022-07-01 /pmc/articles/PMC9464556/ /pubmed/36159134 http://dx.doi.org/10.5826/dpc.1203a125 Text en ©2022 Mahajan et al https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original authors and source are credited. |
spellingShingle | Original Article Mahajan, Sunanda Arun Dave, Jayati Shailesh Dermoscopic Evaluation of Extragenital Lichen Sclerosus et Atrophicus |
title | Dermoscopic Evaluation of Extragenital Lichen Sclerosus et Atrophicus |
title_full | Dermoscopic Evaluation of Extragenital Lichen Sclerosus et Atrophicus |
title_fullStr | Dermoscopic Evaluation of Extragenital Lichen Sclerosus et Atrophicus |
title_full_unstemmed | Dermoscopic Evaluation of Extragenital Lichen Sclerosus et Atrophicus |
title_short | Dermoscopic Evaluation of Extragenital Lichen Sclerosus et Atrophicus |
title_sort | dermoscopic evaluation of extragenital lichen sclerosus et atrophicus |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464556/ https://www.ncbi.nlm.nih.gov/pubmed/36159134 http://dx.doi.org/10.5826/dpc.1203a125 |
work_keys_str_mv | AT mahajansunandaarun dermoscopicevaluationofextragenitallichensclerosusetatrophicus AT davejayatishailesh dermoscopicevaluationofextragenitallichensclerosusetatrophicus |