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Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosis

PURPOSE: Arylamine N-acetyltransferase 1 (NAT1) deficiency has been associated with drug resistance and poor outcomes in breast cancer patients. The current study aimed to investigate drug resistance in vitro using normal breast cancer cell lines and NAT1-deficient cell lines to understand the chang...

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Detalles Bibliográficos
Autores principales:	McAleese, Courtney E., Butcher, Neville J., Minchin, Rodney F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Preclinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464750/ https://www.ncbi.nlm.nih.gov/pubmed/35918499 http://dx.doi.org/10.1007/s10549-022-06668-3

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