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IGF1R signalling is a guardian of self-tolerance restricting autoantibody production

OBJECTIVE: Insulin-like growth factor 1 receptor (IGF1R) acts at the crossroad between immunity and cancer, being an attractive therapeutic target in these areas. IGF1R is broadly expressed by antigen-presenting cells (APC). Using mice immunised with the methylated albumin from bovine serum (BSA-imm...

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Detalles Bibliográficos
Autores principales:	Erlandsson, Malin C., Erdogan, Seval, Wasén, Caroline, Andersson, Karin M. E., Silfverswärd, Sofia T., Pullerits, Rille, Bemark, Mats, Bokarewa, Maria I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464816/ https://www.ncbi.nlm.nih.gov/pubmed/36105797 http://dx.doi.org/10.3389/fimmu.2022.958206

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