Malat1 deficiency prevents hypoxia-induced lung dysfunction by protecting the access to alveoli

Hypoxia is common in lung diseases and a potent stimulator of the long non-coding RNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1). Herein, we investigated the impact of Malat1 on hypoxia-induced lung dysfunction in mice. Malat1-deficient mice and their wild-type littermates were...

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Detalles Bibliográficos
Autores principales: Sallé-Lefort, Sandrine, Miard, Stéphanie, Henry, Cyndi, Arias-Reyes, Christian, Marcouiller, François, Beaulieu, Marie-Josée, Aubin, Sophie, Lechasseur, Ariane, Jubinville, Éric, Marsolais, David, Morissette, Mathieu C., Joseph, Vincent, Soliz, Jorge, Bossé, Ynuk, Picard, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464821/
https://www.ncbi.nlm.nih.gov/pubmed/36105289
http://dx.doi.org/10.3389/fphys.2022.949378

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