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Activity-based protein profiling of human and plasmodium serine hydrolases and interrogation of potential antimalarial targets
Malaria remains a global health issue requiring the identification of novel therapeutic targets to combat drug resistance. Metabolic serine hydrolases are druggable enzymes playing essential roles in lipid metabolism. However, very few have been investigated in malaria-causing parasites. Here, we us...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464883/ https://www.ncbi.nlm.nih.gov/pubmed/36105595 http://dx.doi.org/10.1016/j.isci.2022.104996 |