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Immobilization of modular peptides on graphene cocktail for differentiation of human mesenchymal stem cells to hepatic-like cells

In this study, two novel biomimetic modular peptide motifs based on the alpha-2 subunit of type IV collagen (CO4A2) were designed and immobilized on a graphene platform to imitate integrin and heparan sulfate- (HS-) binding proteins. The in silico study was used to design 9-mer K[KGDRGD]AG and 10-me...

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Detalles Bibliográficos
Autores principales: Adibi-Motlagh, Behzad, Hashemi, Ehsan, Akhavan, Omid, Khezri, Jafar, Rezaei, Aram, Zamani Amir Zakria, Javad, Siadat, Seyed Davar, Sahebghadam Lotfi, Abbas, Farmany, Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465031/
https://www.ncbi.nlm.nih.gov/pubmed/36105306
http://dx.doi.org/10.3389/fchem.2022.943003