Atypical acute disseminated encephalomyelitis with systemic inflammation after a first dose of AztraZaneca COVID-19 vaccine. A case report

BACKGROUND: Only a few cases of acute disseminated encephalomyelitis (ADEM) following coronavirus disease 19 (COVID-19) vaccination have been described since the beginning of the vaccination campaign. RESULTS: Here we report the first case of central nervous system (CNS) demyelination with systemic...

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Autores principales: Bastide, Laure, Perrotta, Gaetano, Lolli, Valentina, Mathey, Céline, Vierasu, Ortensa-Irina, Goldman, Serge, Vandergheynst, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465085/
https://www.ncbi.nlm.nih.gov/pubmed/36105772
http://dx.doi.org/10.3389/fneur.2022.995875
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author Bastide, Laure
Perrotta, Gaetano
Lolli, Valentina
Mathey, Céline
Vierasu, Ortensa-Irina
Goldman, Serge
Vandergheynst, Frédéric
author_facet Bastide, Laure
Perrotta, Gaetano
Lolli, Valentina
Mathey, Céline
Vierasu, Ortensa-Irina
Goldman, Serge
Vandergheynst, Frédéric
author_sort Bastide, Laure
collection PubMed
description BACKGROUND: Only a few cases of acute disseminated encephalomyelitis (ADEM) following coronavirus disease 19 (COVID-19) vaccination have been described since the beginning of the vaccination campaign. RESULTS: Here we report the first case of central nervous system (CNS) demyelination with systemic inflammatory findings on whole body 19-fluorodeoxyglucose positron emission tomography with computed tomography (FDG-PET/CT) following the ChAdOx1 nCoV-19 vaccine. CONCLUSIONS: Clinicians should stay aware of potential new adverse events after immunization.
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spelling pubmed-94650852022-09-13 Atypical acute disseminated encephalomyelitis with systemic inflammation after a first dose of AztraZaneca COVID-19 vaccine. A case report Bastide, Laure Perrotta, Gaetano Lolli, Valentina Mathey, Céline Vierasu, Ortensa-Irina Goldman, Serge Vandergheynst, Frédéric Front Neurol Neurology BACKGROUND: Only a few cases of acute disseminated encephalomyelitis (ADEM) following coronavirus disease 19 (COVID-19) vaccination have been described since the beginning of the vaccination campaign. RESULTS: Here we report the first case of central nervous system (CNS) demyelination with systemic inflammatory findings on whole body 19-fluorodeoxyglucose positron emission tomography with computed tomography (FDG-PET/CT) following the ChAdOx1 nCoV-19 vaccine. CONCLUSIONS: Clinicians should stay aware of potential new adverse events after immunization. Frontiers Media S.A. 2022-08-29 /pmc/articles/PMC9465085/ /pubmed/36105772 http://dx.doi.org/10.3389/fneur.2022.995875 Text en Copyright © 2022 Bastide, Perrotta, Lolli, Mathey, Vierasu, Goldman and Vandergheynst. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Bastide, Laure
Perrotta, Gaetano
Lolli, Valentina
Mathey, Céline
Vierasu, Ortensa-Irina
Goldman, Serge
Vandergheynst, Frédéric
Atypical acute disseminated encephalomyelitis with systemic inflammation after a first dose of AztraZaneca COVID-19 vaccine. A case report
title Atypical acute disseminated encephalomyelitis with systemic inflammation after a first dose of AztraZaneca COVID-19 vaccine. A case report
title_full Atypical acute disseminated encephalomyelitis with systemic inflammation after a first dose of AztraZaneca COVID-19 vaccine. A case report
title_fullStr Atypical acute disseminated encephalomyelitis with systemic inflammation after a first dose of AztraZaneca COVID-19 vaccine. A case report
title_full_unstemmed Atypical acute disseminated encephalomyelitis with systemic inflammation after a first dose of AztraZaneca COVID-19 vaccine. A case report
title_short Atypical acute disseminated encephalomyelitis with systemic inflammation after a first dose of AztraZaneca COVID-19 vaccine. A case report
title_sort atypical acute disseminated encephalomyelitis with systemic inflammation after a first dose of aztrazaneca covid-19 vaccine. a case report
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465085/
https://www.ncbi.nlm.nih.gov/pubmed/36105772
http://dx.doi.org/10.3389/fneur.2022.995875
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