Reversal Of Arterial Disease by modulating Magnesium and Phosphate (ROADMAP-study): rationale and design of a randomized controlled trial assessing the effects of magnesium citrate supplementation and phosphate-binding therapy on arterial stiffness in moderate chronic kidney disease

BACKGROUND: Arterial stiffness and calcification propensity are associated with high cardiovascular risk and increased mortality in chronic kidney disease (CKD). Both magnesium and phosphate are recognized as modulators of vascular calcification and chronic inflammation, both features of CKD that co...

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Detalles Bibliográficos
Autores principales: Vermeulen, Emma A., Eelderink, Coby, Hoekstra, Tiny, van Ballegooijen, Adriana J., Raijmakers, Pieter, Beulens, Joline W., de Borst, Martin H., Vervloet, Marc G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465140/
https://www.ncbi.nlm.nih.gov/pubmed/36096824
http://dx.doi.org/10.1186/s13063-022-06562-9

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