The protective effect of the spleen in sickle cell patients. A comparative study between patients with asplenia/hyposplenism and hypersplenism

Sickle cell disease (SCD) is caused by a point mutation in the beta-globin gene. SCD is characterized by chronic hemolytic anemia, vaso-occlusive events leading to tissue ischemia, and progressive organ failure. Chronic inflammatory state is part of the pathophysiology of SCD. Patients with SCD have...

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Detalles Bibliográficos
Autores principales: Peretz, Sari, Livshits, Leonid, Pretorius, Etheresia, Makhro, Asya, Bogdanova, Anna, Gassmann, Max, Koren, Ariel, Levin, Carina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465245/
https://www.ncbi.nlm.nih.gov/pubmed/36105295
http://dx.doi.org/10.3389/fphys.2022.796837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465245/
https://www.ncbi.nlm.nih.gov/pubmed/36105295
http://dx.doi.org/10.3389/fphys.2022.796837

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