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Application of aptamers in regenerative medicine
Regenerative medicine is a discipline that studies how to use biological and engineering principles and operation methods to repair and regenerate damaged tissues and organs. Until now, regenerative medicine has focused mainly on the in-depth study of the pathological mechanism of diseases, the furt...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465253/ https://www.ncbi.nlm.nih.gov/pubmed/36105606 http://dx.doi.org/10.3389/fbioe.2022.976960 |
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author | Luo, Zhaohui Chen, Shimin Zhou, Jing Wang, Chong Li, Kai Liu, Jia Tang, Yujin Wang, Liqiang |
author_facet | Luo, Zhaohui Chen, Shimin Zhou, Jing Wang, Chong Li, Kai Liu, Jia Tang, Yujin Wang, Liqiang |
author_sort | Luo, Zhaohui |
collection | PubMed |
description | Regenerative medicine is a discipline that studies how to use biological and engineering principles and operation methods to repair and regenerate damaged tissues and organs. Until now, regenerative medicine has focused mainly on the in-depth study of the pathological mechanism of diseases, the further development and application of new drugs, and tissue engineering technology strategies. The emergence of aptamers has supplemented the development methods and types of new drugs and enriched the application elements of tissue engineering technology, injecting new vitality into regenerative medicine. The role and application status of aptamers screened in recent years in various tissue regeneration and repair are reviewed, and the prospects and challenges of aptamer technology are discussed, providing a basis for the design and application of aptamers in long-term transformation. |
format | Online Article Text |
id | pubmed-9465253 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-94652532022-09-13 Application of aptamers in regenerative medicine Luo, Zhaohui Chen, Shimin Zhou, Jing Wang, Chong Li, Kai Liu, Jia Tang, Yujin Wang, Liqiang Front Bioeng Biotechnol Bioengineering and Biotechnology Regenerative medicine is a discipline that studies how to use biological and engineering principles and operation methods to repair and regenerate damaged tissues and organs. Until now, regenerative medicine has focused mainly on the in-depth study of the pathological mechanism of diseases, the further development and application of new drugs, and tissue engineering technology strategies. The emergence of aptamers has supplemented the development methods and types of new drugs and enriched the application elements of tissue engineering technology, injecting new vitality into regenerative medicine. The role and application status of aptamers screened in recent years in various tissue regeneration and repair are reviewed, and the prospects and challenges of aptamer technology are discussed, providing a basis for the design and application of aptamers in long-term transformation. Frontiers Media S.A. 2022-08-29 /pmc/articles/PMC9465253/ /pubmed/36105606 http://dx.doi.org/10.3389/fbioe.2022.976960 Text en Copyright © 2022 Luo, Chen, Zhou, Wang, Li, Liu, Tang and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Bioengineering and Biotechnology Luo, Zhaohui Chen, Shimin Zhou, Jing Wang, Chong Li, Kai Liu, Jia Tang, Yujin Wang, Liqiang Application of aptamers in regenerative medicine |
title | Application of aptamers in regenerative medicine |
title_full | Application of aptamers in regenerative medicine |
title_fullStr | Application of aptamers in regenerative medicine |
title_full_unstemmed | Application of aptamers in regenerative medicine |
title_short | Application of aptamers in regenerative medicine |
title_sort | application of aptamers in regenerative medicine |
topic | Bioengineering and Biotechnology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465253/ https://www.ncbi.nlm.nih.gov/pubmed/36105606 http://dx.doi.org/10.3389/fbioe.2022.976960 |
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