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Engineering enhanced thermostability into the Geobacillus pallidus nitrile hydratase
Nitrile hydratases (NHases) are important biocatalysts for the enzymatic conversion of nitriles to industrially-important amides such as acrylamide and nicotinamide. Although thermostability in this enzyme class is generally low, there is not sufficient understanding of its basis for rational enzyme...
Autores principales: | Van Wyk, Jennifer C., Sewell, B. Trevor, Danson, Michael J., Tsekoa, Tsepo L., Sayed, Muhammed F., Cowan, Don A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465369/ https://www.ncbi.nlm.nih.gov/pubmed/36106339 http://dx.doi.org/10.1016/j.crstbi.2022.07.002 |
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