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LncRNA GAS5 represses stemness and malignancy of gliomas via elevating the SPACA6-miR-125a/let-7e Axis
Glioblastoma (GBM) is a highly invasive neurological malignancy with poor prognosis. LncRNA-GAS5 (growth arrest-specific transcript 5) is a tumor suppressor involved in multiple cancers. In this study, we explored the clinical significance, biological function, and underlying mechanisms of GAS5 in G...
Autores principales: | Wu, Shuang, Ren, Kaixi, Zhao, Jing, Li, Juan, Jia, Bo, Wu, Xiuquan, Dou, Yanan, Fei, Xiaowei, Huan, Yu, He, Xin, Wang, Tingting, Lv, Weihao, Wang, Li, Wang, Yan’gang, Zhao, Junlong, Fei, Zhou, Li, Sanzhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465381/ https://www.ncbi.nlm.nih.gov/pubmed/36106122 http://dx.doi.org/10.3389/fonc.2022.803652 |
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