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Computational study of the impact of nucleotide variations on highly conserved proteins: In the case of actin

Sequencing of individual human genomes enables studying relationship among nucleotide variations, amino acid substitutions, effect on protein structures and diseases. Many studies have found general tendencies, for instance, that pathogenic variations tend to be found in the buried regions of the pr...

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Detalles Bibliográficos
Autores principales: Duong, Ha T. T., Suzuki, Hirofumi, Katagiri, Saki, Shibata, Mayu, Arai, Misae, Yura, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465404/
https://www.ncbi.nlm.nih.gov/pubmed/36160324
http://dx.doi.org/10.2142/biophysico.bppb-v19.0025