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Computational study of the impact of nucleotide variations on highly conserved proteins: In the case of actin
Sequencing of individual human genomes enables studying relationship among nucleotide variations, amino acid substitutions, effect on protein structures and diseases. Many studies have found general tendencies, for instance, that pathogenic variations tend to be found in the buried regions of the pr...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society of Japan
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465404/ https://www.ncbi.nlm.nih.gov/pubmed/36160324 http://dx.doi.org/10.2142/biophysico.bppb-v19.0025 |