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Integration of healthy volunteers in early phase clinical trials with immuno-oncological compounds
AIM: Traditionally, early phase clinical trials in oncology have been performed in patients based on safety risk-benefit assessment. Therapeutic transition to immuno-oncology may open new opportunities for studies in healthy volunteers, which are conducted faster and are less susceptible to confound...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465458/ https://www.ncbi.nlm.nih.gov/pubmed/36106110 http://dx.doi.org/10.3389/fonc.2022.954806 |