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Optineurin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration

Low back pain is thought to be mainly caused by intervertebral disc degeneration (IVDD), and there is a lack of effective treatments. Cellular senescence and matrix degradation are important factors that cause disc degeneration. Mitochondrial dysfunction induced by oxidative stress is an important m...

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Detalles Bibliográficos
Autores principales:	Hu, Zhilei, Wang, Yu, Gao, Xiaoxin, Zhang, Yuyao, Liu, Chenhao, Zhai, Yu, Chang, Xian, Li, Haiyin, Li, Yueyang, Lou, Jinhui, Li, Changqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465714/ https://www.ncbi.nlm.nih.gov/pubmed/36105191 http://dx.doi.org/10.3389/fphar.2022.893307

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