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Elesclomol: a copper ionophore targeting mitochondrial metabolism for cancer therapy
Elesclomol is an anticancer drug that targets mitochondrial metabolism. In the past, elesclomol was recognized as an inducer of oxidative stress, but now it has also been found to suppress cancer by inducing cuproptosis. Elesclomol’s anticancer activity is determined by the dependence of cancer on m...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465867/ https://www.ncbi.nlm.nih.gov/pubmed/36089608 http://dx.doi.org/10.1186/s13046-022-02485-0 |