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Metformin reverse minocycline to inhibit minocycline-resistant Acinetobacter baumannii by destroy the outer membrane and enhance membrane potential in vitro

BACKGROUND: Acinetobacter baumannii (A. baumannii) is an opportunistic pathogen and has emerged as one of the most troublesome pathogens. Drug resistance in A. baumannii has been reported on a global scale. Minocycline was found to be active against multi-drug resistant A. baumannii and was approved...

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Detalles Bibliográficos
Autores principales: Guo, Tingting, Sun, Xiaoli, Yang, Jie, Yang, Liying, Li, Mengying, Wang, Yuhang, Jiao, Hongmei, Li, Guocai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465895/
https://www.ncbi.nlm.nih.gov/pubmed/36089583
http://dx.doi.org/10.1186/s12866-022-02629-4