Single nucleotide polymorphism genes and mitochondrial DNA haplogroups as biomarkers for early prediction of knee osteoarthritis structural progressors: use of supervised machine learning classifiers

BACKGROUND: Knee osteoarthritis is the most prevalent chronic musculoskeletal debilitating disease. Current treatments are only symptomatic, and to improve this, we need a robust prediction model to stratify patients at an early stage according to the risk of joint structure disease progression. Som...

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Detalles Bibliográficos
Autores principales: Bonakdari, Hossein, Pelletier, Jean-Pierre, Blanco, Francisco J., Rego-Pérez, Ignacio, Durán-Sotuela, Alejandro, Aitken, Dawn, Jones, Graeme, Cicuttini, Flavia, Jamshidi, Afshin, Abram, François, Martel-Pelletier, Johanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465912/
https://www.ncbi.nlm.nih.gov/pubmed/36089590
http://dx.doi.org/10.1186/s12916-022-02491-1

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