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Myeloid liver kinase B1 contributes to lung inflammation induced by lipoteichoic acid but not by viable Streptococcus pneumoniae
BACKGROUND: Liver kinase B1 (Lkb1, gene name Stk11) functions as a tumor suppressor in cancer. Myeloid cell Lkb1 potentiates lung inflammation induced by the Gram-negative bacterial cell wall component lipopolysaccharide and in host defense during Gram-negative pneumonia. Here, we sought to investig...
Autores principales: | Pereverzeva, Liza, Otto, Natasja A., Roelofs, Joris J. T. H., de Vos, Alex F., van der Poll, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465928/ https://www.ncbi.nlm.nih.gov/pubmed/36096803 http://dx.doi.org/10.1186/s12931-022-02168-6 |
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