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On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects

Polyether-ether-ketone (PEEK) is widely used in producing prosthesis and have gained great attention for repair of large bone defect in recent years with the development of additive manufacturing. This is due to its excellent biocompatibility, good heat and chemical stability and similar mechanical...

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Autores principales: Naghavi, Seyed Ataollah, Sun, Changning, Hejazi, Mahbubeh, Tamaddon, Maryam, Zheng, Jibao, Wang, Leilei, Zhang, Chenrui, Varma, Swastina Nath, Li, Dichen, Moazen, Mehran, Wang, Ling, Liu, Chaozong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Medical Multimedia Press Co., Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465988/
https://www.ncbi.nlm.nih.gov/pubmed/36105563
http://dx.doi.org/10.12336/biomatertransl.2022.02.006
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author Naghavi, Seyed Ataollah
Sun, Changning
Hejazi, Mahbubeh
Tamaddon, Maryam
Zheng, Jibao
Wang, Leilei
Zhang, Chenrui
Varma, Swastina Nath
Li, Dichen
Moazen, Mehran
Wang, Ling
Liu, Chaozong
author_facet Naghavi, Seyed Ataollah
Sun, Changning
Hejazi, Mahbubeh
Tamaddon, Maryam
Zheng, Jibao
Wang, Leilei
Zhang, Chenrui
Varma, Swastina Nath
Li, Dichen
Moazen, Mehran
Wang, Ling
Liu, Chaozong
author_sort Naghavi, Seyed Ataollah
collection PubMed
description Polyether-ether-ketone (PEEK) is widely used in producing prosthesis and have gained great attention for repair of large bone defect in recent years with the development of additive manufacturing. This is due to its excellent biocompatibility, good heat and chemical stability and similar mechanical properties which mimics natural bone. In this study, three replicates of rectilinear scaffolds were designed for compression, tension, three-point bending and torsion test with unit cell size of 0.8 mm, a pore size of 0.4 mm, strut thickness of 0.4 mm and nominal porosity of 50%. Stress-strain graphs were developed from experimental and finite element analysis models. Experimental Young’s modulus and yield strength of the scaffolds were measured from the slop of the stress-strain graph to be 395 and 19.50 MPa respectively for compression, 427 and 6.96 MPa respectively for tension, 257 and 25.30 MPa respectively for three-point bending and 231 and 12.83 MPa respectively for torsion test. The finite element model was found to be in good agreement with the experimental results. Ductile fracture of the struct subjected to tensile strain was the main failure mode of the PEEK scaffold, which stems from the low crystallinity of additive manufacturing PEEK. The mechanical properties of porous PEEK are close to those of cancellous bone and thus are expected to be used in additive manufacturing PEEK bone implants in the future, but the lower yield strength poses a design challenge
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spelling pubmed-94659882022-09-13 On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects Naghavi, Seyed Ataollah Sun, Changning Hejazi, Mahbubeh Tamaddon, Maryam Zheng, Jibao Wang, Leilei Zhang, Chenrui Varma, Swastina Nath Li, Dichen Moazen, Mehran Wang, Ling Liu, Chaozong Biomater Transl Research Article Polyether-ether-ketone (PEEK) is widely used in producing prosthesis and have gained great attention for repair of large bone defect in recent years with the development of additive manufacturing. This is due to its excellent biocompatibility, good heat and chemical stability and similar mechanical properties which mimics natural bone. In this study, three replicates of rectilinear scaffolds were designed for compression, tension, three-point bending and torsion test with unit cell size of 0.8 mm, a pore size of 0.4 mm, strut thickness of 0.4 mm and nominal porosity of 50%. Stress-strain graphs were developed from experimental and finite element analysis models. Experimental Young’s modulus and yield strength of the scaffolds were measured from the slop of the stress-strain graph to be 395 and 19.50 MPa respectively for compression, 427 and 6.96 MPa respectively for tension, 257 and 25.30 MPa respectively for three-point bending and 231 and 12.83 MPa respectively for torsion test. The finite element model was found to be in good agreement with the experimental results. Ductile fracture of the struct subjected to tensile strain was the main failure mode of the PEEK scaffold, which stems from the low crystallinity of additive manufacturing PEEK. The mechanical properties of porous PEEK are close to those of cancellous bone and thus are expected to be used in additive manufacturing PEEK bone implants in the future, but the lower yield strength poses a design challenge Chinese Medical Multimedia Press Co., Ltd 2022-06-28 /pmc/articles/PMC9465988/ /pubmed/36105563 http://dx.doi.org/10.12336/biomatertransl.2022.02.006 Text en https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work noncommercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Research Article
Naghavi, Seyed Ataollah
Sun, Changning
Hejazi, Mahbubeh
Tamaddon, Maryam
Zheng, Jibao
Wang, Leilei
Zhang, Chenrui
Varma, Swastina Nath
Li, Dichen
Moazen, Mehran
Wang, Ling
Liu, Chaozong
On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects
title On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects
title_full On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects
title_fullStr On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects
title_full_unstemmed On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects
title_short On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects
title_sort on the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465988/
https://www.ncbi.nlm.nih.gov/pubmed/36105563
http://dx.doi.org/10.12336/biomatertransl.2022.02.006
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