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On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects
Polyether-ether-ketone (PEEK) is widely used in producing prosthesis and have gained great attention for repair of large bone defect in recent years with the development of additive manufacturing. This is due to its excellent biocompatibility, good heat and chemical stability and similar mechanical...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chinese Medical Multimedia Press Co., Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465988/ https://www.ncbi.nlm.nih.gov/pubmed/36105563 http://dx.doi.org/10.12336/biomatertransl.2022.02.006 |
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author | Naghavi, Seyed Ataollah Sun, Changning Hejazi, Mahbubeh Tamaddon, Maryam Zheng, Jibao Wang, Leilei Zhang, Chenrui Varma, Swastina Nath Li, Dichen Moazen, Mehran Wang, Ling Liu, Chaozong |
author_facet | Naghavi, Seyed Ataollah Sun, Changning Hejazi, Mahbubeh Tamaddon, Maryam Zheng, Jibao Wang, Leilei Zhang, Chenrui Varma, Swastina Nath Li, Dichen Moazen, Mehran Wang, Ling Liu, Chaozong |
author_sort | Naghavi, Seyed Ataollah |
collection | PubMed |
description | Polyether-ether-ketone (PEEK) is widely used in producing prosthesis and have gained great attention for repair of large bone defect in recent years with the development of additive manufacturing. This is due to its excellent biocompatibility, good heat and chemical stability and similar mechanical properties which mimics natural bone. In this study, three replicates of rectilinear scaffolds were designed for compression, tension, three-point bending and torsion test with unit cell size of 0.8 mm, a pore size of 0.4 mm, strut thickness of 0.4 mm and nominal porosity of 50%. Stress-strain graphs were developed from experimental and finite element analysis models. Experimental Young’s modulus and yield strength of the scaffolds were measured from the slop of the stress-strain graph to be 395 and 19.50 MPa respectively for compression, 427 and 6.96 MPa respectively for tension, 257 and 25.30 MPa respectively for three-point bending and 231 and 12.83 MPa respectively for torsion test. The finite element model was found to be in good agreement with the experimental results. Ductile fracture of the struct subjected to tensile strain was the main failure mode of the PEEK scaffold, which stems from the low crystallinity of additive manufacturing PEEK. The mechanical properties of porous PEEK are close to those of cancellous bone and thus are expected to be used in additive manufacturing PEEK bone implants in the future, but the lower yield strength poses a design challenge |
format | Online Article Text |
id | pubmed-9465988 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Chinese Medical Multimedia Press Co., Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-94659882022-09-13 On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects Naghavi, Seyed Ataollah Sun, Changning Hejazi, Mahbubeh Tamaddon, Maryam Zheng, Jibao Wang, Leilei Zhang, Chenrui Varma, Swastina Nath Li, Dichen Moazen, Mehran Wang, Ling Liu, Chaozong Biomater Transl Research Article Polyether-ether-ketone (PEEK) is widely used in producing prosthesis and have gained great attention for repair of large bone defect in recent years with the development of additive manufacturing. This is due to its excellent biocompatibility, good heat and chemical stability and similar mechanical properties which mimics natural bone. In this study, three replicates of rectilinear scaffolds were designed for compression, tension, three-point bending and torsion test with unit cell size of 0.8 mm, a pore size of 0.4 mm, strut thickness of 0.4 mm and nominal porosity of 50%. Stress-strain graphs were developed from experimental and finite element analysis models. Experimental Young’s modulus and yield strength of the scaffolds were measured from the slop of the stress-strain graph to be 395 and 19.50 MPa respectively for compression, 427 and 6.96 MPa respectively for tension, 257 and 25.30 MPa respectively for three-point bending and 231 and 12.83 MPa respectively for torsion test. The finite element model was found to be in good agreement with the experimental results. Ductile fracture of the struct subjected to tensile strain was the main failure mode of the PEEK scaffold, which stems from the low crystallinity of additive manufacturing PEEK. The mechanical properties of porous PEEK are close to those of cancellous bone and thus are expected to be used in additive manufacturing PEEK bone implants in the future, but the lower yield strength poses a design challenge Chinese Medical Multimedia Press Co., Ltd 2022-06-28 /pmc/articles/PMC9465988/ /pubmed/36105563 http://dx.doi.org/10.12336/biomatertransl.2022.02.006 Text en https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work noncommercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Research Article Naghavi, Seyed Ataollah Sun, Changning Hejazi, Mahbubeh Tamaddon, Maryam Zheng, Jibao Wang, Leilei Zhang, Chenrui Varma, Swastina Nath Li, Dichen Moazen, Mehran Wang, Ling Liu, Chaozong On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects |
title | On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects |
title_full | On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects |
title_fullStr | On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects |
title_full_unstemmed | On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects |
title_short | On the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects |
title_sort | on the mechanical aspect of additive manufactured polyether-ether-ketone scaffold for repair of large bone defects |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465988/ https://www.ncbi.nlm.nih.gov/pubmed/36105563 http://dx.doi.org/10.12336/biomatertransl.2022.02.006 |
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