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A tissue-engineered artificial human thymus from human iPSCs to study T cell immunity
A tissue engineering method using a 3D scaffolding enables the generation of an artificial human thymus from inducible pluripotent stem cells (iPSCs). The artificial thymus can be used to study human T cell development in hematopoietic humanized mice.
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Nature Publishing Group US
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466301/ https://www.ncbi.nlm.nih.gov/pubmed/36097212 http://dx.doi.org/10.1038/s41592-022-01584-2 |
| _version_ | 1784787961276006400 |
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| collection | PubMed |
| description | A tissue engineering method using a 3D scaffolding enables the generation of an artificial human thymus from inducible pluripotent stem cells (iPSCs). The artificial thymus can be used to study human T cell development in hematopoietic humanized mice. |
| format | Online Article Text |
| id | pubmed-9466301 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | Nature Publishing Group US |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-94663012022-09-12 A tissue-engineered artificial human thymus from human iPSCs to study T cell immunity Nat Methods Research Briefing A tissue engineering method using a 3D scaffolding enables the generation of an artificial human thymus from inducible pluripotent stem cells (iPSCs). The artificial thymus can be used to study human T cell development in hematopoietic humanized mice. Nature Publishing Group US 2022-09-12 2022 /pmc/articles/PMC9466301/ /pubmed/36097212 http://dx.doi.org/10.1038/s41592-022-01584-2 Text en © Springer Nature America, Inc. 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
| spellingShingle | Research Briefing A tissue-engineered artificial human thymus from human iPSCs to study T cell immunity |
| title | A tissue-engineered artificial human thymus from human iPSCs to study T cell immunity |
| title_full | A tissue-engineered artificial human thymus from human iPSCs to study T cell immunity |
| title_fullStr | A tissue-engineered artificial human thymus from human iPSCs to study T cell immunity |
| title_full_unstemmed | A tissue-engineered artificial human thymus from human iPSCs to study T cell immunity |
| title_short | A tissue-engineered artificial human thymus from human iPSCs to study T cell immunity |
| title_sort | tissue-engineered artificial human thymus from human ipscs to study t cell immunity |
| topic | Research Briefing |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466301/ https://www.ncbi.nlm.nih.gov/pubmed/36097212 http://dx.doi.org/10.1038/s41592-022-01584-2 |