Relationship between ER expression by IHC or mRNA with Ki67 response to aromatase inhibition: a POETIC study

BACKGROUND: In clinical practice, oestrogen receptor (ER) analysis is almost entirely by immunohistochemistry (IHC). ASCO/CAP recommends cut-offs of < 1% (negative) and 1–10% (low) cells positive. There is uncertainty whether patients with ER low tumours benefit from endocrine therapy. We aimed t...

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Detalles Bibliográficos
Autores principales: Lopez-Knowles, Elena, Detre, Simone, Hills, Margaret, Schuster, Eugene F., Cheang, Maggie C. U., Tovey, Holly, Kilburn, Lucy S., Bliss, Judith M., Robertson, John, Mallon, Elizabeth, Skene, Anthony, Evans, Abigail, Smith, Ian, Dowsett, Mitch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466340/
https://www.ncbi.nlm.nih.gov/pubmed/36096872
http://dx.doi.org/10.1186/s13058-022-01556-6

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