Perinatal versus adult loss of ULK1 and ULK2 distinctly influences cardiac autophagy and function

Impairments in macroautophagy/autophagy, which degrades dysfunctional organelles as well as long-lived and aggregate proteins, are associated with several cardiomyopathies; however, the regulation of cardiac autophagy remains insufficiently understood. In this regard, ULK1 and ULK2 are thought to pl...

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Detalles Bibliográficos
Autores principales: Harris, Matthew P., Zhang, Quan J., Cochran, Cole T., Ponce, Jessica, Alexander, Sean, Kronemberger, Ana, Fuqua, Jordan D., Zhang, Yuan, Fattal, Ranan, Harper, Tyler, Murry, Matthew L., Grueter, Chad E., Abel, E. Dale, Lira, Vitor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9466614/
https://www.ncbi.nlm.nih.gov/pubmed/35104184
http://dx.doi.org/10.1080/15548627.2021.2022289

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