Alpha-Chymotrypsin Protects Against Acute Lung, Kidney, and Liver Injuries and Increases Survival in CLP-Induced Sepsis in Rats Through Inhibition of TLR4/NF-κB Pathway

ABSTRACT: Inflammation and oxidative stress play a major role in the development of sepsis and its associated complications, leading to multiple organ failure and death. The lungs, liver, and kidneys are among the early affected organs correlated with mortality in sepsis. Alpha-chymotrypsin (α-ch) i...

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Detalles Bibliográficos
Autores principales: Senousy, Shaymaa Ramzy, Ahmed, Al-Shaimaa F, Abdelhafeez, Dalia A, Khalifa, Mohamed Montaser A, Abourehab, Mohammed A S, El-Daly, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9467300/
https://www.ncbi.nlm.nih.gov/pubmed/36105322
http://dx.doi.org/10.2147/DDDT.S370460

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